Yea the colors should be kept in mind. Usually neutral colors do very well and shades of the same color do very well and are easy on the eyes. For example the use of the color green in this forum theme, it uses a variety of greens and creates an overall appealing design. The website creator should also make sure that if they put adverts on their website that they don't make it too overbearing that no one wants to visit. As there is suc a thing as TOO many ads. haha